Sunday, November 24, 2024

Itching

I probably shouldn’t have delved into this topic. It’s horribly complicated. I was curious about the fact that I have an itchy spot under my left collar bone (hard to reach!). My little itch is small potatoes compared to the suffering that many people endure.

Dermatology websites list the causes of itching: extremely dry skin; bug bites; skin conditions, such as eczema, hives, and psoriasis; skin cancer; warning signs of diseases, especially of the kidney and liver, and overactive thyroid gland; allergic skin reaction; reaction to a plant or marine life; medication or cancer treatment; nerve problem. Scratching alleviates itch by interrupting it: the pain of scratching creates the pleasure of relief.

One in five people experience chronic itch in their lifetime, often caused by cancer, a skin condition, or liver or kidney disease. (There are no medications for it.) Some unlucky people have a rare disease in which itching can be unrelenting and extreme.

The kind of itching that’s acute (not chronic), and caused by irritants such as poison ivy, is caused by the immune system’s reactions: immune cells secrete histamine that activates the nervous system, making you itch and scratch. Medications, such as steroids or antihistamines, may help in these cases. Some people itch for no clear reason and their bodies don’t respond to steroids or antihistamines.

In 2007, neuroscientists figured out itch-specific nerve receptors that are triggered by substances other than histamines. Some itching—such as that caused eczema—is caused by the body’s secretion of certain proteins (cytokines) that rev up the immune system. In 2017, the FDA approved a drug called Dupixent, which reduces the immune system's overreaction that causes eczema. Apparently, it works. It can be yours for $59,000 a year (retail).

My research yielded nothing in the way of explanation for my little itch--at least nothing definitive. I can live with it.

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1 comment:

  1. Another cause for itching is diabetes, and lots of older people have that issue. A hot shower really fees good, but it is not good for dry itchy skin.Using anti itch lotion does help dry skin.

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