Sunday, September 24, 2017

“Good cholesterol” not that great; “bad cholesterol not so bad”

Supposedly you want your HDL cholesterol level to be high and your LDL cholesterol level to be low.  HDL is supposedly the “good cholesterol” and LDL is the “bad cholesterol.” Doctors knock themselves out trying to raise their patients’ HDL levels and lower their LDL levels. This is looking to be misguided (as I’ve said all along). A recent study in the European Heart Journal followed more than 116,000 men and women for an average of six years. They found that men with an HDL level of 73 milligrams per deciliter had the lowest all-cause mortality; those with a level of 97 to 115 had a 36 percent increase risk for death. That is, those with the lower level were less likely to die than those with the higher level. This is the reverse of what we’ve been told (although if your HDL is very low—under 39—that’s not a good thing either).

LDL cholesterol is supposedly the “bad” cholesterol. In a systematic review of studies that looked at mortality of people over 60 found an inverse relationship between the level of LDL cholesterol and mortality. “We didn´t find any study having shown that high LDL-cholesterol is a risk factor for elderly people.”   In other words, those people over 60 with high LDL lived the longest.

Well, some studies have shown you can prolong your life by taking statin drugs—by about four days. Researchers from the University of Southern Denmark did a systematic review of all statin trials that compared statin treatment to a placebo. For people who were treated as a preventive measure, the average postponement of death was 3.2 days; for people who had already had a heart attack, death was postponed by an average of 4.1 days. The trial that showed the longest postponement of death, that postponement was 27 days. In the trial with the worst outcome, life was shortened by an average of 10 days.
Just forget the whole business and don’t worry about your cholesterol.

For an introduction to this blog, see I Just Say No; for a list of blog topics, click the Topics tab.

No comments:

Post a Comment