From 1968 until 1973 Dr. Ivan Frantz Jr. of the University
of Minnesota Medical School conducted a controlled clinical trial comparing diets containing saturated fats with those containing vegetable oils and no saturated fats. He hoped to prove that replacing saturated fat, such as butter and other animal
fats, with corn oil would protect
them against heart disease and lower their mortality. The research subjects
lived in mental hospitals and a nursing home where diets can be strictly
regulated. Half the subjects were fed meals rich in saturated fats from milk,
cheese and beef; the others ate a diet where the fat consisted of corn oil. The
result: the participants who ate the low saturated fat diet reduced their
cholesterol by an average of 14 percent. Nevertheless, the low-saturated fat diet did not reduce mortality. In fact, the
study showed the greater drop in
cholesterol, the higher risk of death during the trial.
Even though this research was one of the largest controlled
clinical trials ever conducted, the data were never fully analyzed or
published. In fact, they’d been virtually hidden away and were only recently
discovered in a dusty box by Dr. Frantz’s son (Frantz senior died in 2009). “My
father definitely believed in reducing saturated fats,” he said, noting also
that his father was probably startled by what seemed to be no benefit in
replacing saturated fat with vegetable oil. In other words, the trial results
were a disappointment.
While some nutritionists protest these findings, which have
recently been published in the journal BMJ, plenty of other scientists find
support for them. For example, one scientists analyzed four similar trials in
which vegetable oils were substituted for animal fats. Those trials also failed
to show any reduction in mortality from heart disease. In 2013, Dr. Christopher
Ramsden, who is a medical investigator for the National Institutes of Health,
discovered a similar trial that been carried out in Australia in the 1960s, but
also had not been fully analyzed or published. Like the others, the results
showed that those who replaced saturated fat with vegetable oils lowered their
cholesterol, but were also more likely to die from a heart attack than the
control group who ate more saturated fat. “One would expect that the more you lowered
cholesterol, the better the outcome. But in this case the opposite association
was found. The greater degree of cholesterol-lowering was associated with a
higher, rather than lower, risk of death.”
I love this. For a long time, I have believed that those who
have instilled a fear of saturated fat and cholesterol have done us a terrible
disservice. Because I get quite exercised about these topics, you can find more
posts about them: one on why I refuse cholesterol checks and one on the misinformation about saturated fat.
For an introduction to this blog, see I Just Say No; for a list of blog topics, click the Topics tab.
For an introduction to this blog, see I Just Say No; for a list of blog topics, click the Topics tab.
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